"Osteogenesis Imperfecta..." 

...literally means "bone that is imperfectly made from the beginning of life." OI is a genetic disorder of type 1 collagen-- the protein "scaffolding" of bone and other connective tissues. People with OI have a faulty gene that instructs their bodies to make either too little type 1 collagen or a poor quality type 1 collagen. The result is that bones break easily.


Fast Facts
Basic information about the disorder, the categories of OI, and the number of people affected. 

Glossary
A list of selected terms and phrases related to OI, genetics and research. 
 

Introduction To OI
This 12-page pamphlet includes basic information about the disorder, including characteristics, diagnosis, common myths, inheritance factors, basic treatment strategies, and precautions for medical professionals caring for patients with OI.
Download the pamphlet now.
View the text in your web browser.
Order multiple copies through the
 online store.


Understanding Bone Structure
A more in-depth look at how the disorder affects the bones, but this document is still written for the layman.

 

Child Abuse Issues
The milder forms of the disorder are very difficult to diagnose-- learn how OI may present as Child Abuse, and how to tell the difference. 



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