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...literally means "bone that is imperfectly made from the beginning of life." OI is a genetic disorder of type 1 collagen-- the protein "scaffolding" of bone and other connective tissues. People with OI have a faulty gene that instructs their bodies to make either too little type 1 collagen or a poor quality type 1 collagen. The result is that bones break easily. |
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Fast Facts A list of selected terms and phrases related to OI, genetics and research. |
Introduction To OI |
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Understanding Bone Structure |
Child Abuse Issues |